Changes of thromboxane B2 in surgical operations.
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چکیده
منابع مشابه
Peroxisomal chain-shortening of thromboxane B2: evidence for impaired degradation of thromboxane B2 in Zellweger syndrome.
We have shown that rat liver peroxisomes can chain-shorten prostaglandins to dinor- and tetranor-metabolites. In a recent in vivo study we could demonstrate that peroxisomes are of major importance for chain-shortening of prostaglandin F2 alpha in humans (1991, Diczfalusy et al. J. Clin. Invest. 88:978-984). This was shown by identifying the major urinary metabolites of radiolabeled prostagland...
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[3H8]Thromboxane B2 was biosynthesized and infused into an unanesthetized monkey. Several urinary metabolites were isolated and their structures elucidated using gas chromatography-mass spectrometry. In addition to the major urinary metabolite, dinor-thromboxane B2, a series of metabolites resulting from dehydrogenetion of the alcohol group at C-11 were identified: 11-dehydro-thromboxane B2, 11...
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The hemodynamic properties of thromboxane B2 (TxB2), a product of prostaglandin endoperoxide metabolism, have not been thoroughly described. TxB2 is a bronchoconstrictor, but its effects on the systemic circulation and circulating platelets are unknown. Its precursor, thromboxane A2(TxA2), is a potent vasoconstrictor as well as a platelet-aggregating agent. Using intact anesthetized dogs, we in...
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Thromboxane B2 (TXB2) is the stable metabolite of thromboxane A2 (TXA2), a potent vasoconstrictor which induces irreversible platelet aggregation. The inhibition of TXA2 by aspirin and other agents has been associated with improved outcome following cerebral ischemia in clinical and laboratory studies. To investigate the relation of TXA2 production to cerebral ischemia, we measured the urinary ...
متن کاملEffect of ethanol on gastric secretion of thromboxane B2.
Correspondence: W. P. Fung University Department of Medicine Royal Perth Hospital Box X2213 GPO, Perth Western Australia 6001 Several natural prostaglandins and their synthetic analogues have been shown to have marked effects on gastric function.l l Prostaglandin E 2 and its 15(R) 15 methyl analogue have been shown to be effective in the promotion of gastric ulcer healing. 1z 1 6 Furthermore, s...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1985
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.16.172